Agree with the above "see a doctor".
If normal stuff e.g. Gaviscon not controlling it, and long standing/ongoing heartburn symptoms just see your GP*

*I actually AM a doctor & OTC PPIs make me uncomfortable as people with serious problems then buy it for years and don't come and tell us!

I used to buy this until my GP prescribed the same thing on repeat, the generic esomeorazole 56 tablets a month for £10 via the NHS PPC scheme.

heat, however...

1. go and see your doctor,
2. these can affect other drugs, e.g. letting anti diahorrea (opiates) drugs to cross the gut into your blood.

I take oneperazole

I would not recommend this medication to anyone who can manage on standard antacids. Once your body gets used to them on a daily basis they're a nightmare to come off. Ideal for those who find they get no relief from those though...and a decent price. (This is my experience only and I take PPIs twice a day).

i need this.

I used to buy this until my GP prescribed the same thing on repeat, the generic esomeorazole 56 tablets a month for £10 via the NHS PPC scheme.

​I'm tea total, took the two together and felt noticeably trippy/tipsy. After googling found anecdotal suggestions that this was the cause. I haven't found any formal interaction documentation but as loperamide isn't a long term drug I was guessing tests may not have been done. I imagine pharma will test the obvious drugs but will not test all combinations as that would be prohibitive.

Loperamide is a long term drug for some people - as is a loperamide/omeprazole/codeine combination - which I have been taking for 4 years

​further reading, omeperazole also inhibits P-glycoprotein, this is associated with BBB blocking loperamide. I'm no expert, doctor or junkie so I might have just felt lightheaded after the squits.... :confused: