Agree with the above "see a doctor".
If normal stuff e.g. Gaviscon not controlling it, and long standing/ongoing heartburn symptoms just see your GP*

*I actually AM a doctor & OTC PPIs make me uncomfortable as people with serious problems then buy it for years and don't come and tell us!

I used to buy this until my GP prescribed the same thing on repeat, the generic esomeorazole 56 tablets a month for £10 via the NHS PPC scheme.

heat, however...

1. go and see your doctor,
2. these can affect other drugs, e.g. letting anti diahorrea (opiates) drugs to cross the gut into your blood.

I take oneperazole

I would not recommend this medication to anyone who can manage on standard antacids. Once your body gets used to them on a daily basis they're a nightmare to come off. Ideal for those who find they get no relief from those though...and a decent price. (This is my experience only and I take PPIs twice a day).

i need this.

I used to buy this until my GP prescribed the same thing on repeat, the generic esomeorazole 56 tablets a month for £10 via the NHS PPC scheme.

​I'm tea total, took the two together and felt noticeably trippy/tipsy. After googling found anecdotal suggestions that this was the cause. I haven't found any formal interaction documentation but as loperamide isn't a long term drug I was guessing tests may not have been done. I imagine pharma will test the obvious drugs but will not test all combinations as that would be prohibitive.

Loperamide is a long term drug for some people - as is a loperamide/omeprazole/codeine combination - which I have been taking for 4 years

​further reading, omeperazole also inhibits P-glycoprotein, this is associated with BBB blocking loperamide. I'm no expert, doctor or junkie so I might have just felt lightheaded after the squits.... :confused:

Not doubting you, was simply curious.

No, Nexium have the rights to it for a period of time I believe may be a good while before we see supermarkets doing own brand versions like we get with analgesics and NSAIDs

used to take these then switched to decaff coffee and havent needed them since. I am not a big coffee drinker but cutting out caffine cured me of acid reflux.

heat for price good old amazon :innocent:

Esomeprazole (Nexium) is patented, but omeprazole is a generic drug. If your doctor attempts to prescribe you esomeprazole, you should insist on omeprazole.* They are ridiculously close to being the same drug (there were claims of evergreening on the manufacturer's part), but the former currently costs the NHS almost three times the latter.

I've seen esomeprazole for sale in supermarkets, and omeprazole for sale on pharmacy shelves. Pick whichever is cheaper; currently you still pay multiples of what the NHS pays irrespective of patents.

* I'm not a doctor, etc.

Top tip for heartburn when going to bed, sleep on your left handside....thank me later :wink:

long term it's thought can increase fracture risk, increase susceptibility to c diff bug, hypomagnesemia.

Agree with the above "see a doctor".
If normal stuff e.g. Gaviscon not controlling it, and long standing/ongoing heartburn symptoms just see your GP*

*I actually AM a doctor & OTC PPIs make me uncomfortable as people with serious problems then buy it for years and don't come and tell us!

Do, what he says. Just go see a doctor. They are there to help you and one should not feel embarassed about any issues we may have.

I've been on a PPI for about 10 years now, currently Pantoprazole 20mg a day 56 tablets on repeat, go see your quack if you need a PPI.

​nexium will go generic soon, patent has (or is just about to) expire

As said above take these for a while and you will be stuck on them, try coming off them and acid rebound will be worse than it was before, better off with Zantac

Haha. Well that's a fair argument for a week or 2 but not 6-12months. As it happens I don't work in a traditional GP setup. People I see called for an appointment never more than 6hrs earlier. Often within an hour. Sadly huge numbers of appointments in GP wasted by people with a cold who want a "cure". Or who don't show up (although I like those, it's called catch up time!)

Esomeprazole is generic now (ie cheap but just as good). Theoretically decreases effectiveness of platelet blocker clopidogrel. As others have said, ranitidine is cheaper and 98% as good. You won't get withdrawal (rebound) acid unless you've been on them for a long time. Goose112 - you've tested negative for h. pylori bacteria that cause ulcers but it doesn't mean you don't have acid reflux. Pressure on GPs to not prescribe antacids. Start with Gaviscon over the counter.