The precise mechanism of alcohol is not fully understood yet, it definitely has a GABAgenic effect. Severe Valium withdrawal symptoms include grand mal seizures. Experimental compounds to reduce tolerance and reduce withdrawals are Agmatine and Fasoracetam.

Doesn't alcohol do pretty much the same thing? And have these valium induced seizures ever killed anyone, like alcohol induced seizures have? Honest question.

Might it be the case like with alcohol that in order to develop seizures from withdrawal you have to be severely dependent on the substance? I'm not suggesting it's not addictive or dangerous mind, just that the danger it poses needs to be put into context.

Valium is definitely a highly addictive substance, however not everyone will suffer addiction to it. Valium is prescribed for other medical disorders as well as anxiety. The human brain is wired for addiction via Delta FOSB gene expression, although in the case of Valium (Diazepam) the addiction potential is most definitely physical due to the underlying mechanisms involved. Valium causes rapid down regulation of GABA A sub units and homeostatis within the brain means that GABA receptors sub units are desensitised. Removing exogenous positive allosteric modulation of GABA A subunits via Valium (stopping taking Valium without tapering) means that GABA receptor upregulation and sensitivity is now massively out of balance and without a means to prevent Glutamate excitotoxicity causing seizures and massive increase in anxiety over baseline. All this means that continuous longer term consumption of Valium can produce strong addiction potential.

Valium is hard to come off but I wouldn't say it's 'highly addictive', it's probably less addictive than alcohol which don't get me wrong is quite addictive too. It's just by saying 'highly addictive' you make it sound like heroin.

The biggest problem with valium in my opinion is not necessarily the valium itself but the alcohol or other CNS depressants that people mix it with. Sadly that's how most people die.

There's good and bad doctors. A friend of mine with bad addiction problems to hard drugs has just been given a small script for Diazepam (Valium), that is something I don't understand at all, it's a highly addictive drug. I know full well that he'll take the 10 x 2mg pills in one day, yet it's supposed to last him a month. I felt like trying to ask them what they're thinking, it doesn't seem rational at all.

It's just what I was advised by doctors after I told them I'd bought a blood pressure monitor. To be honest I normally take what doctors say to me with a grain of salt.

You can see though how compressing an artery so that blood flow stops momentarily is probably not good for you if you do it to excess.

And no one here is saying that it's a bad idea to monitor your blood pressure, it's just not advisable to do it to excess. However, it's a better idea to do it to excess than not at all.

"Regularly is okay but frequently is not good for you."

What does this mean? Does it mean that taking your blood pressure frequently has a physical impact on your health by the nature of taking the measurements, or rather a mental toll? If it's the latter then it could be argued that globally the assertion it's not good for you is false.

"Have gearbest finally gotten over their biggest crutch?"

That they have the sh****t customer service known to mankind?
No.

Was looking for one with Heart Rate and Blood Pressure - this isn't it.

It probably changed after to ordered, like literally. I was at Paypal, but decided to go back to basket (I'd initially selected Paypal with credit card, but went back for just Paypal -I've never known them be offered seperate like that before) and after changing it saud the flash sale was over. They must have had alot of clicks and just closed it.

Always reluctant to order from Gearbest as you havd to ho though Paypal when thrre's a problem (which is ususlly often)

A piece of advice for any new customers. When it goes wrong and Gearbest promise you it thry will reship or refund if you close your dispute, don't. You have know comeback after

Buy it from the Uk at the higher price :/

any solution please?

http://uk.gearbest.com/smart-wristband/pp_180798.html?wid=42

£14.75 UK stock if you cant be bothered waiting from China

sorry i am wrong you are right

I stand corrected!! :smiley:

same issue persists even in Incognite mode :disappointed:..Can't order

:smiley: but coming back to shopping cart when clicking on "Pay". Unable to order

Appreciate the info, that may work out cheaper than buying a new handset!

Can anyone confirm if this will work with a Windows phone? I have read the description and it doesn't mention Windows mobile support, I could take that as it doesn't. I'm going to have to get a new phone if that's the case!

Expired

Just ordered xioami mi band 2 $21.99 looked on YouTube looks good

Don't really want one but ordered x

The order doesn't seem to have gone through. Some error with the order processing :-(

ordered for a tenner, worth a punt.

Thanks for the info - I'll have to give that a try!

And tested again. Shows correct price with countdown. Add to basket and price in basket is increased with message "Sorry,flash sale is over."

When I went to basket it said "sorry, the flash sale has ended"

thanks op - ordered one just cos i couldn't resist! -
might work out what to do with it when it comes :-(

I know it is under £8, any one have any experience, the Mi band gets good reviews on here and I was just about to click and order when saw this.

Found Xiaomi Yeelight RGBW E27 Smart LED Bulb in the flash sale £11.93 UK or £13.27 China.Great bulb thanks op.

Ordered TY OP

Expired

£7.95 only if ordered via china warehouse. £14.95 from EU Warehouse

7.71 if you pay in dollars with Revolut app

Every little helps