Don't know if it's as effective as alcepin caffeine but worth a bash. Sarky comments won't touch my egg head sides
Top comments
MrWani
4 Feb 1710#2
Clinically proven to achieve diddly squat.
machomansavage
4 Feb 176#6
UPDATE: come outta bath after trying it out. Now look like John Travolta from Saturday night fever, and Mrs can't stop running her fingers through my locks!. Forgot to add earlier this stuff is 3.99 plus P&P of 2.99 on amazon and 3.95 on eBay. So all in all great deal from Home Bargains!
Master.G to red23
5 Feb 174#25
I made that mistake.
fishmaster
4 Feb 173#13
Only three things work for hairloss:
Minoxidil a topical application, approved for hair loss, works by largely unknown mechanism possibly via Nitric Oxide production.
Finasteride - Also approved for hairloss. A Dihydrotestosterone inhibitor via 5 alpha reductase enzyme type 2 inhibition. An all round bad idea, considering the effect on neurosteroid biosynthesis. Could lead to persistent mental health problems such as depression and anxiety.
Dustasteride: Not approved, but essentially a more powerful version of Finasteride because it also inhibits type 1 and 2 5 alpha reductase not just just type 2.
Anything else is experimental and unproven. My advice go bald and learn to like it :smiley:
Latest comments (34)
Master.G
6 Feb 171#32
I've found this to be by far the most effective treatment for handling hair loss.
machomansavage to Master.G
6 Feb 17#34
Bloody grand father has one of these hats!
HereKittyKitty
6 Feb 17#31
Before you go around saying what is and isn't statistically significant, you need to understand what statistical significance is. It's not a matter of simply having the most participants (although it helps), but rather a set of mathematical analyses applied to a dataset. It's an academic discipline in its own right, and one that any second-year biologist will be expected to learn. If you check the final paragraph of the first page, you'll notice that they did perform a statistical analysis and found their results to be... statistically significant.
Your self-reporting, heterogeneous pool of hair loss forum members aren't likely to stick around after their hair loss has stabilised or reversed, which may explain why you mistakenly believe that only 3 treatments are proven to work.
That said, ketoconazole is obviously not a wonder drug and - like all these treatments - is unlikey to reverse years of male pattern baldness in old, shiny-headed men.
fishmaster to HereKittyKitty
6 Feb 17#33
I think we're both right in a sense, studies are complex, they are the only method we have to judge scientific observation, unfortunately they're open to abuse and often are and the science can be flawed. It's all we really have though. Possibly peer review/meta-analysis is better, it's still not perfect.
"It’s also important to remember that, even though a finding may be statistically significant, it might not be meaningful. For example, if you tested a new user interface with 100 participants and found they were able to complete a task 2% faster, the result would be statistically significant, but not necessarily meaningful enough to act upon."
"For comparative studies—which are typically more objective than problem-discovery studies because of their heavy reliance on metrics—group sizes of between eight and 25 participants typically provide valid results, with ten to twelve being a good baseline. Generally, group size should increase if you want statistically significant results; punctuated studies can be an efficient way of achieving this goal."
My advice if you wish to treat hairloss is accept it, if you can't accept it then use Minoxidil and Finasteride or Dutasteride, you can't halt the progress indefinitely though. Ketaconazole isn't worth the effort. If you have enough donor hair and enough money, you can move your hair from one place to another, so you can move the genetically immune follicles in place of genetically susceptible follicles the best method appears to be FUE (Follicular Unit Extraction), you can get it done cheaper in other countries than the UK, the plane fare included.
fishmaster
5 Feb 17#30
It's not demonstrably false, also it's not the world we're living in now, in fact this world we live in has an expanse of knowledge and availability that no other generation has experienced. I can tell you that from 20+ years experience in the hair loss community Ketaconazole is useless. Also that study you cite has a participant pool of just 6 people, statistically the study is useless as well. I can't find one statistically significant study that shows Ketaconazole is effective as a hair loss treatment and I've never seen great results from anyone using Ketaconazole. If it has an effect it has a very minor effect. Also just as the Serotonin model of depression is flawed so is the DHT model of hair loss or rather poorly understood.
thebdaman
5 Feb 17#29
Interestingly, this is apparently the choice of treatment for the leader of the free world....
HereKittyKitty
5 Feb 17#28
It's strange how you say that with such conviction despite it being demonstrably false
But I suppose that's the world we're living-in now
And, without tooting my own horn, I am actually very qualified to talk about this
machomansavage
5 Feb 171#27
fishmaster
5 Feb 17#26
Ketoconazole is useless. Azelaic acid makes your head go red and if you're none responder to Minoxidil it won't help you. Spironolactone can be mixed with NAC, not something you want having any internal effect. Isotretinoin doesn't stop or regrow hair. As I've stated there are no effective hair loss treatments in existence, apart from experimental ones that most people can't obtain and possibly have bad side effects.
While the the vitamin companies hardly make any money, and are only interested in making us healthy... :smirk:
machomansavage
4 Feb 176#6
UPDATE: come outta bath after trying it out. Now look like John Travolta from Saturday night fever, and Mrs can't stop running her fingers through my locks!. Forgot to add earlier this stuff is 3.99 plus P&P of 2.99 on amazon and 3.95 on eBay. So all in all great deal from Home Bargains!
Locknloadharry to machomansavage
4 Feb 171#8
Now you will have to change your name to ManSausageAdonis....off you go!
bozo007 to machomansavage
5 Feb 171#21
Then you should also use Simpson Caffe Latte shaving cream. It isn't cheap but works wonders since my wife loves coffee. :stuck_out_tongue:
Edged
5 Feb 17#20
Vitamins have been proven to work and have helped many ill people, the reason they don't want you to think they help is they don't want everyone to be healthy, I mean there's no big profit in that for the rich
fishmaster
4 Feb 173#13
Only three things work for hairloss:
Minoxidil a topical application, approved for hair loss, works by largely unknown mechanism possibly via Nitric Oxide production.
Finasteride - Also approved for hairloss. A Dihydrotestosterone inhibitor via 5 alpha reductase enzyme type 2 inhibition. An all round bad idea, considering the effect on neurosteroid biosynthesis. Could lead to persistent mental health problems such as depression and anxiety.
Dustasteride: Not approved, but essentially a more powerful version of Finasteride because it also inhibits type 1 and 2 5 alpha reductase not just just type 2.
Anything else is experimental and unproven. My advice go bald and learn to like it :smiley:
thecresta to fishmaster
4 Feb 17#16
Finasteride was a prostate cancer treatment that was discovered to also slow or stop hair loss. In all cases, you're experimenting on yourself. The benefits and side effects for each of these drugs are different for everyone, and the long term effects of them are unknown.
HereKittyKitty to fishmaster
5 Feb 17#19
Not quite. Caffeine is proven to work, just not very well. If you added it to topical minoxidil, it would stay on your head longer and it would have a cumulative effect, but it won't do much by itself.
There's also ketoconazole, available as a shampoo (Nizoral), which has been shown to work very well.
Then there's spironolactone, azelaic acid, isotretinoin and a load of other things. Some are very dangerous and none of them work particularly well by themselves (at least not in small enough doses to avoid side effects). I think the trick is to take as many different treatments as you reasonably can.
HereKittyKitty
5 Feb 171#18
I meant anhydrous caffeine, obv :laughing:
therealclaireh
5 Feb 17#17
Apparently these caffeine shampoos don't stay on your head long enough to be of any real benefit, in comparison to Alpecin and Plantur prices it's a bargain
RedRain
4 Feb 171#15
if this really worked it would be £20 a bottle like dick enlargement pills fat pills ect
Babbler
4 Feb 171#14
Who cares its 95p. Worth a go lol.
Like wash and go... :wink:
HereKittyKitty
4 Feb 17#10
This is a good price compared to Alpecin, but you could just buy some caffeine powder and put it in your regular shampoo. It's very soluble
thecresta to HereKittyKitty
4 Feb 17#12
And you'd get that lovely coffee house smell throughout the day.
Good price compared to Alcepin, and likely just as effective...
AbdulAbz
4 Feb 17#11
Will this help wake up in the morning shower ?
machomansavage
4 Feb 17#9
Haha great!
MrWani
4 Feb 1710#2
Clinically proven to achieve diddly squat.
Locknloadharry to MrWani
4 Feb 171#7
Just like all vitamins....totally bereft of clinical evidence to support well- being.
snowflake75
4 Feb 173#5
just rub on a cup of nescafe
davidridge1
4 Feb 171#4
Hair today, gone tomorrow.
dunno
4 Feb 173#3
I prefer
onelifeliveit369
4 Feb 171#1
I've found this in Poundland stores and Poundstretcher Newcastle/ Gateshead recently £1 its selling on Amazon too £3.95!
I think it's great cleans hair really well..and the caffeine to stimulate hair roots, keratin to strengthen hair...I'm a woman with long hair I don't know any women who don't want thicker stronger hair...worth a go! Alpecin similar product sells for 6 times that at £5.99. Hot from me!
Opening post
Top comments
Minoxidil a topical application, approved for hair loss, works by largely unknown mechanism possibly via Nitric Oxide production.
Finasteride - Also approved for hairloss. A Dihydrotestosterone inhibitor via 5 alpha reductase enzyme type 2 inhibition. An all round bad idea, considering the effect on neurosteroid biosynthesis. Could lead to persistent mental health problems such as depression and anxiety.
Dustasteride: Not approved, but essentially a more powerful version of Finasteride because it also inhibits type 1 and 2 5 alpha reductase not just just type 2.
Anything else is experimental and unproven. My advice go bald and learn to like it :smiley:
Latest comments (34)
Your self-reporting, heterogeneous pool of hair loss forum members aren't likely to stick around after their hair loss has stabilised or reversed, which may explain why you mistakenly believe that only 3 treatments are proven to work.
That said, ketoconazole is obviously not a wonder drug and - like all these treatments - is unlikey to reverse years of male pattern baldness in old, shiny-headed men.
http://www.uxmatters.com/mt/archives/2016/01/how-to-determine-the-right-number-of-participants-for-usability-studies.php
"It’s also important to remember that, even though a finding may be statistically significant, it might not be meaningful. For example, if you tested a new user interface with 100 participants and found they were able to complete a task 2% faster, the result would be statistically significant, but not necessarily meaningful enough to act upon."
"For comparative studies—which are typically more objective than problem-discovery studies because of their heavy reliance on metrics—group sizes of between eight and 25 participants typically provide valid results, with ten to twelve being a good baseline. Generally, group size should increase if you want statistically significant results; punctuated studies can be an efficient way of achieving this goal."
My advice if you wish to treat hairloss is accept it, if you can't accept it then use Minoxidil and Finasteride or Dutasteride, you can't halt the progress indefinitely though. Ketaconazole isn't worth the effort. If you have enough donor hair and enough money, you can move your hair from one place to another, so you can move the genetically immune follicles in place of genetically susceptible follicles the best method appears to be FUE (Follicular Unit Extraction), you can get it done cheaper in other countries than the UK, the plane fare included.
http://207.194.174.56/docs/nizoral_shampoo_ketoconazole_2_hair_loss.pdf
But I suppose that's the world we're living-in now
And, without tooting my own horn, I am actually very qualified to talk about this
:smirk:
Minoxidil a topical application, approved for hair loss, works by largely unknown mechanism possibly via Nitric Oxide production.
Finasteride - Also approved for hairloss. A Dihydrotestosterone inhibitor via 5 alpha reductase enzyme type 2 inhibition. An all round bad idea, considering the effect on neurosteroid biosynthesis. Could lead to persistent mental health problems such as depression and anxiety.
Dustasteride: Not approved, but essentially a more powerful version of Finasteride because it also inhibits type 1 and 2 5 alpha reductase not just just type 2.
Anything else is experimental and unproven. My advice go bald and learn to like it :smiley:
There's also ketoconazole, available as a shampoo (Nizoral), which has been shown to work very well.
Then there's spironolactone, azelaic acid, isotretinoin and a load of other things. Some are very dangerous and none of them work particularly well by themselves (at least not in small enough doses to avoid side effects). I think the trick is to take as many different treatments as you reasonably can.
Like wash and go... :wink:
Good price compared to Alcepin, and likely just as effective...
I think it's great cleans hair really well..and the caffeine to stimulate hair roots, keratin to strengthen hair...I'm a woman with long hair I don't know any women who don't want thicker stronger hair...worth a go! Alpecin similar product sells for 6 times that at £5.99. Hot from me!